20+ years engineering vectors/gene therapies
Casey Maguire is a scientific co-founder and consultant of Skylark Bio. He obtained his Ph.D. in Microbiology and Immunology from the University of Rochester School of Medicine and Dentistry in 2006. Dr. Maguire is a virus vector bioengineer by training, with over 23 years of experience, first working with adenoviruses for his doctoral work and with adeno-associated virus (AAV) vectors. He is an Associate Professor Neurology at Harvard Medical School and Principal Investigator at the Massachusetts General Hospital.
He has published over 50 peer-reviewed papers, mainly in the field of vector gene delivery and therapy and has 5 issued US patents related to biotechnology, including novel AAV-based gene delivery systems. Together with collaborator and neurobiologist, Dr. David Corey at HMS, they have developed and tested novel AAV systems for gene delivery and therapy in mouse models of deafness and in 2018 demonstrated that AAV could efficiently transduce the inner ear of non-human primates.